The Manx flag is due to blast into space later.
Nicole Stott is part of the crew of the Space Shuttle Discovery's final mission, which is scheduled to launch this evening.
The astonaut is married to Manxman Chris Stott, the boss of ManSat.
Whilst at the International Space Station on a previous mission, Nicole linked-up with a class of school children on the Isle of Man to talk about her experience in space.
Discovery has circled the earth more than 5000 times.
Shuttle Launch Director Michael Leinbach admits it will be an emotional moment [play clip]